Activase

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Activase

What is Activase
?

Activase (alteplase) is a thrombolytic agent used to dissolve blood clots in the body. It is used to treat a type of heart attack called a ST-segment elevation myocardial infarction (STEMI), and to prevent blood clots in the lungs (pulmonary embolism).

Benefits of Activase
and Its Uses.

Activase (alteplase) is a thrombolytic drug used to dissolve blood clots. It is used to treat a heart attack, stroke, and pulmonary embolism.

Activase is a recombinant human tissue-type plasminogen activator (t-PA) that is produced in a laboratory. t-PA is a naturally occurring enzyme that helps dissolve blood clots. Activase is used to treat a heart attack, stroke, and pulmonary embolism.

Activase is given by injection.

Heart attack: Activase is used to dissolve blood clots that have formed in the coronary arteries. It is given to patients who have had a heart attack and who are still having chest pain.

Stroke: Activase is used to dissolve blood clots that have formed in the brain. It is given to patients who have had a stroke and who are still having problems with movement, speech, or understanding.

Side Effects and Dosage of Activase

Activase (alteplase) is a thrombolytic agent used to treat acute myocardial infarction (AMI) and acute ischemic stroke. It is a recombinant human tissue plasminogen activator (tPA) that is administered intravenously.

Activase is indicated for the treatment of AMI caused by thrombotic coronary artery occlusion. It is also indicated for the treatment of acute ischemic stroke caused by intracranial large artery occlusion.

The recommended dosage of Activase for the treatment of AMI is 100 mg administered as a bolus over two minutes, followed by an infusion of 18 mg/hr for up to 72 hours.

The recommended dosage of Activase for the treatment of acute ischemic stroke is 100 mg administered as a bolus over two minutes, followed by an infusion of 0.9 mg/kg/hr for up to 24 hours.

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