Afamelanotide Subcutaneous


Afamelanotide Subcutaneous

What is Afamelanotide Subcutaneous

Afamelanotide is a synthetic, injectable peptide hormone drug. It is used to treat erythropoietic protoporphyria, a rare disorder that results in extreme sensitivity to sunlight. Afamelanotide is a melanocyte-stimulating hormone analog that is thought to improve skin pigmentation and protect the skin from UV damage. It is administered by subcutaneous injection.

Benefits of Afamelanotide Subcutaneous
and Its Uses.

Afamelanotide (SC) is a synthetic peptide analogue of alpha-melanocyte stimulating hormone (alpha-MSH) that is under development for the treatment of a range of skin disorders, including erythropoietic protoporphyria (EPP), vitiligo, and melanoma.

Afamelanotide is a pro-drug that is converted to the active form, alpha-MSH, after administration. It is thought that the primary mode of action of afamelanotide is to stimulate the production of melanin by melanocytes, leading to increased skin pigmentation.

Clinical studies have shown that afamelanotide is effective in the treatment of EPP. In a phase III clinical trial, afamelanotide was shown to be superior to placebo in the reduction of EPP symptoms, including pain, itch, and photophobia.

Afamelanotide has also been shown to be effective in the treatment of vit

Side Effects and Dosage of Afamelanotide Subcutaneous

Afamelanotide (Subcutaneous) is a melanocyte stimulating hormone analog indicated for the prevention of erythema nodosum leprosum (ENL) in patients with leprosy. It is supplied as a subcutaneous injection.

Common side effects of Afamelanotide (Subcutaneous) include:

– Nausea
– Vomiting
– Headache
– Dizziness
– Fatigue
– Skin irritation at the injection site

Rare but serious side effects of Afamelanotide (Subcutaneous) include:

– Severe allergic reaction (anaphylaxis)
– Swelling of the face, lips, tongue, or throat
– Difficulty breathing
– Chest pain
– Rapid heartbeat
– Seizure

There is no specific dosage information for Afamelanotide (Subcutaneous) available. It is generally administered as a single subcutaneous injection of 0.5

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