What is Antithrombin III
Antithrombin III (AT-III) is a protein that helps to prevent blood clotting. It does this by blocking the action of certain clotting factors (proteins that promote blood clotting). Antithrombin III is produced by the body and is also available as a medication.
AT-III is used to prevent blood clots in people who have conditions that increase their risk of blood clots, such as:
-Deep vein thrombosis (DVT)
-Pulmonary embolism (PE)
-Atherosclerosis (a condition that causes fatty deposits to build up inside the arteries)
AT-III is also used to prevent blood clots in people who are having surgery.
Benefits of Antithrombin III
and Its Uses.
Antithrombin III (AT III) is a naturally occurring enzyme found in the blood that helps to prevent blood clots. It is made up of a heavy chain and a light chain, which are connected by a disulfide bond. The heavy chain contains two domains, the N-terminal domain and the C-terminal domain. The light chain contains the reactive site.
AT III is produced by the liver and is found in the blood plasma. It is also present in the synovial fluid, which is the fluid that surrounds the joints.
AT III circulates in the blood in an inactive form. When a blood clot forms, thrombin is produced. Thrombin is a protein that helps to convert fibrinogen, a protein in the blood, into fibrin, which is the main component of a blood clot. Fibrinogen is converted into fibrin by the action of two proteins, thrombin and Stuart
Side Effects and Dosage of Antithrombin III
Antithrombin III (AT III) is a medication prescribed to prevent blood clots. It is a natural protein that is produced by the body. It works by blocking the activity of certain clotting factors in the blood. AT III is available as a prescription medication and can also be obtained as a natural product derived from human plasma.
The most common side effects of AT III include: headache, nausea, vomiting, diarrhea, and fever. Less common side effects include: chest pain, shortness of breath, and swelling of the feet or ankles.
AT III is available in tablet form and the usual dose is 1,000 units per day.