What is Pacritinib
Pacritinib is a drug that is used to treat a certain type of blood cancer. It is a pill that is taken by mouth. Pacritinib is used to treat myelofibrosis, a type of cancer that affects the bone marrow. Myelofibrosis causes the bone marrow to produce too many cells, which can crowd out healthy blood cells and lead to anemia, fatigue, and other problems. Pacritinib works by blocking the action of a protein called JAK2. This protein is involved in the growth and development of cancer cells. By blocking JAK2, pacritinib may stop or slow the growth of cancer cells.
Benefits of Pacritinib
and Its Uses.
Pacritinib (trade name: PEGASYS) is a novel medication used to treat chronic myelofibrosis (CMF), a rare bone marrow disorder. It is a type of tyrosine kinase inhibitor (TKI), a class of drugs that block the activity of enzymes that promote cancer growth.
Pacritinib was approved by the United States Food and Drug Administration (FDA) in February 2018 for the treatment of adults with CMF. It is the first TKI approved for the treatment of CMF.
Pacritinib is taken by mouth as a tablet. It is usually taken twice a day with food.
The most common side effects of pacritinib include nausea, diarrhea, vomiting, tiredness, and fever.
Pacritinib may cause serious side effects, including heart attack, stroke, and death. It is important to tell your doctor about any side effects you experience.
Side Effects and Dosage of Pacritinib
Pacritinib is a medication used to treat a number of conditions, including myelofibrosis, polycythemia vera, and rheumatoid arthritis. It belongs to a class of drugs called kinase inhibitors. Pacritinib is available as a tablet and can be taken with or without food.
Common side effects of pacritinib include diarrhea, nausea, vomiting, and abdominal pain. Pacritinib can also cause a decrease in white blood cell count, so patients may be at risk for infection. It can also cause a decrease in platelet count, so patients may be at risk for bleeding.
Pacritinib is not recommended for pregnant women or women who are breastfeeding. It can cause harm to a developing fetus or newborn baby.
Pacritinib should not be taken by people with a history of severe liver disease. It can cause serious liver damage.
The recommended dose of pacritinib is