What is Pegloticase
Pegloticase is an enzyme that breaks down uric acid. It is used to treat gout.
Benefits of Pegloticase
and Its Uses.
Pegloticase is a uric acid specific enzyme, which is used to decrease the levels of uric acid in the blood. It is a biologic drug, which is made from human cells. Pegloticase is used to treat gout, which is a type of arthritis that is caused by high levels of uric acid in the blood. When uric acid levels are high, it can cause crystals to form in the joints, which can lead to pain, inflammation, and swelling.
Pegloticase is approved to treat adults with gout who have not been able to lower their uric acid levels with other treatments, such as allopurinol. Pegloticase is given as an infusion into a vein (IV) every two weeks.
Pegloticase can help to lower uric acid levels and relieve symptoms of gout. It is important to know that peglicase is not a cure for gout and
Side Effects and Dosage of Pegloticase
Pegylated uricase, trade name Pegloticase, is a medication used to treat high levels of uric acid in the blood, a condition called hyperuricemia. Uric acid is a waste product of the body’s metabolism of protein. When the level of uric acid in the blood becomes too high, it can cause crystals of uric acid to form in the joints, leading to a condition called gout. Pegloticase is a pegylated form of the enzyme uricase, which breaks down uric acid. By breaking down uric acid into allantoin, a less harmful substance, pegoloticase can help to decrease the levels of uric acid in the blood and reduce the symptoms of gout.
Pegloticase is given by injection into a vein. It is usually given every two weeks.
Pegloticase can cause side effects such as nausea, vomiting, diarrhea, and chest pain